Veterinarian
The Best Doctor In The World Is A Veterinarian He Can,t Ask His Patients What Is The Matter He,s Go To Just Know
Healthcare
You may not appreciate the presence of good health, but you will definitely regret the absence of good health, because health is happiness.”
Hacking
The hacker community may be small, but it possesses the skills that are driving the global economies of the future.
Showing posts with label 2nd semester. Show all posts
Showing posts with label 2nd semester. Show all posts
Monday, 16 June 2014
Syllabus Of BIOCHEMISTRY OF METABOLISM
BIOCHEMISTRY OF METABOLISM
2(2-0)
THEORY
Introduction of metabolism, Glycolysis, regulation, and
energy production, Kreb‟s cycle, regulation and energy production, Pentose
phosphate shunt, Glucoronic acid pathway, Glucogensis, glycogensis,
glycogenolysis, gluconeogensis, Metabolism of fructose, galactose and lactose,
Introduction to protein metabolism and plasma amino acidsSynthesis of
non-essential amino acids, Fate of ammonia and keto-acids, Urea cycle and its
importance, glutathione and creatinine formation, Catabolism of non-essential
amino acids,Introduction to lipid metabolism, Beta-oxidation of even
chained-fatty acids, Beta-oxidation of odd-chained fatty acids, Omega-oxidation
of fats, Alpha-oxidation of fats, Oxidation of respiratory chain, Biosynthesis
of fatty acids, Biosynthesis of triglycerides,Biosynthesis of triglycerides,
Biosynthesis of prostaglandins, Biosynthesis of cholesterol, Factors affecting
cholesterol level in plasma,Transportation of lipids, Role of adipose tissue in
fat metabolism, Ketogensis and use of ketone bodies, Metabolism of bile salts
and bile acids, Intermediary metabolism of carbohydrates, fats and proteins,
23
Bioenergetics, Introduction to fermentation, Use of
agro-industrial wastes for production of antibiotics, enzymes and steroids,
1. Ahmad Mushtaq, A. (2003). essential of medical
biochemistry, Vol !, 7th Ed. Ilmi book house urdu bazaar, Lahore
2. Murrary, R. K, D. K. Granner, P.A Mayes and V.W Redwell.
(2000). Harper‟s Biochemistry, 25th Ed. Appleton & Lange Inc. USA
3. Stryer, L. 1995. Biochemistry. W. H. Freemen Pub. Co.
USA.
4. Nelson, D. L & M M. Cox (2000). Leheninger Principles
of Biochemistry. 3rd Ed., Livingston Pub, Inc, USA.
5. Brown, T. A. (2001). Gene cloning and DNA analysis: An
Introduction. 4th Ed. Blackwell science Ltd., U.K.
Saturday, 7 June 2014
Subjects Of 2nd semester
Subjects Of 2nd semester
|
COURSE NO.
|
COURSE TITLE
|
Contact Hours
|
||||
|
|
Theory Practical
|
|||||
|
ANAT
|
Comparative Anatomy
|
1
|
6
|
|||
|
ANAT
|
Systemic Veterinary Histology
|
1
|
4
|
|||
|
MICRO
|
General Veterinary
Microbiology
|
2
|
2
|
|||
|
PHYSIOL
|
Physiology of Digestion and
Lactation
|
2
|
2
|
|||
|
BIOCHEM
|
Biochemistry of Metabolism
|
2
|
0
|
|||
|
ABG
|
Introduction to Animal
Breeding and Genetics
|
3
|
2
|
|||
|
AN
|
Principles of Animal
Nutrition
|
2
|
2
|
|||
|
SS
|
Pakistan Studies
|
1
|
0
|
|||
|
Total
|
14
|
18
|
||||
Wednesday, 1 May 2013
Lecture 1 Physiology 2nd Semester
Introduction To Gastrointestinal Physiology
n DIGESTIVE
SYSTEM
n In
simple terms, the digestive system is a portal for nutrients to gain access to
the circulatory system.
► Foodstuffs
are broken down to very simple molecules.
► Resulting
sugars, amino acids, fatty acids, etc. are then transported across the GI tract
lining into blood.
► The
specific foodstuffs animals are able to utilize is dependent on the type of
digestive system they possess.
n Three
(3) basic types of digestive systems:
► Monogastric
– simple stomach.
► Ruminant
(cranial fermentor) – multi-compartmented stomach.
► Hind
gut (caudal) fermentor – simple stomach, but very large and complex large
intestine
Basic Functional Anatomy of the
Digestive System
– Monogastrics
– Monogastrics
n Organs of the Digestive System
– Monogastrics
– Monogastrics
n Mouth
► Mechanical breakdown of foodstuffs by
chewing (reduces particle size, increases surface area for action of enzymes).
►
Saliva added as a lubricant and, in some species, contains amylase to
begin starch digestion.
► Esophagus
► Tube connecting the mouth to the
stomach.
n Stomach
► Enzymatic digestion of proteins
begins.
► Foodstuffs reduced to liquid form.
► Liver
► Center of metabolic activity in the
body.
► Major role in digestive process is to
provide bile salts to small intestine (needed for digestion and absorption of
fats).
n Pancreas
► Provides a potent mixture of
digestive enzymes to the small intestine to help in digestion of fats,
carbohydrates, and proteins.
► Small Intestine
► 3 sections – duodenum, jejunum, ileum
► Site of final stages of chemical
enzymatic digestion.
► Where almost all nutrients are
absorbed.
n Large Intestine
► 3 sections – cecum, colon, rectum
► Site of water absorption from G.I.
tract.
► Bacterial fermentation occurs
(production and absorption of volatile fatty acids).
P Somewhat limited in monogastrics
► Feces formed.
Specialized Organs in Poultry
n Beak
► No lips, no teeth, and no chewing.
► Crop
► Out-pocketing of the esophagus that
provides storage for consumed food.
► Foodstuffs moistened and softened
(little if any digestion).
n Proventriculus
►
Glandular
stomach where the first significant amount of digestive juices are added.
n Gizzard
► A muscular organ used to grind and
break up food.
►
May
contain grit (small stones) eaten by animal.
n Cloaca
► Common chamber into which the
digestive, urinary, and reproductive tracts open.
► When
fecal material is excreted, the cloaca folds back at the vent allowing the
rectal opening of the large intestine to push out, closing the reproductive
tract opening.
Basic Functional Anatomy of the
Digestive System
– Ruminants –
– Ruminants –
« Mouth, esophagus, liver, pancreas,
gall bladder, small intestine, and large intestine have functions similar to
monogastrics.
« Ruminants
produce prodigious quantities of saliva. Published estimates for adult cows are
in the range of 100 to 150 liters of saliva per day! Aside from its normal
lubricating qualities, saliva serves at least two very important functions in
the ruminant:
« provision of fluid for the
fermentation vat
« alkaline buffering - saliva is rich
in bicarbonate, which buffers the large quanitity of acid produced in the rumen
and is probably critical for maintainance of rumen pH.
« Stomach
« Structure and function of the stomach
is the major difference between monogastrics and ruminants.
Multi-compartmented stomach – rumen, reticulum, omasum,
abomasum
n Rumen:
► Large,
anaerobic fermentation vat.
n Rumen (continued):
► Houses microorganisms.
n Protozoa
– 100,000 per gram of rumen fluid.
n Bacteria/fungi
– 100 million per gram of rumen fluid.
► Functions of microorganisms.
n Digest
roughages to make Volatile Fatty Acids (VFA’s), make
microbial protein, and make vitamins K and B-complex.
► VFA’s absorbed in rumen.
► Lined
with millions of papillae (short projections on wall of rumen) needed for
absorption.
► “Shag
carpet” appearanc
n Rumen
saturated with gases and in constant motion.
n Contractions
occur at a rate of 1-3 per minute.
► Serve
to mix contents, aid in eructation of gases, and move fluid and fermented
feedstuffs into the omasum.
n Rumination:
►
Ruminants are well known for “cud
chewing”.
► Rumination
involves:
n Bolus
of previously eaten foodstuff carried back into the mouth by reverse
peristalsis.
n Fluid
in bolus is squeezed out with the tongue and reswallowed.
n Bolus
is rechewed and reswallowed.
► Rumination
may occupy about 1/3 of a ruminant’s day
n Eructation (belching):
► Fermentation
of foodstuffs in the rumen generates enormous quantities of gas.
n 30-50
liters per hour in adult cattle.
n 5-7
liters per hour in adult sheep or goats.
► Belching
is how ruminants get rid of fermentation gases:
n Anything
that causes a hindrance to belching can be life threatening.
n Bloating
can result in death from asphyxiation.
n Reticulum:
► Contains
microorganisms (like the rumen).
► Provides
additional area for fermentation.
► As
fermentation by microorganisms proceed and feedstuffs are digested, smaller and
more dense material is pushed into the reticulum (from which it along with
microbe-laden liquid is ejected into the omasum).
► Lining
has a honeycomb structure.
n Catches
and holds hardware consumed by animal.
n Hardware
can be removed with rumen magnate.
n Omasum:
► A
heavy, hard organ with a lining that has many folds (leaves).
► Function not well understood.
► Believed
to produce a grinding action on foodstuffs.
► May
absorb residual VFA’s and bicarbonate.
n Abomasum:
► The
true, glandular stomach.
n Secretes
acids and functions very similarly to monogastric stomach.
► Unique
feature is that it secretes lysozyme.
n Enzyme
that efficiently breaks down bacterial cell walls.
n Needed
to break down the large quantities of bacteria that pass from the rumen.
n Basic Functional Anatomy of the Digestive System
– Hind Gut Fermentors –
– Hind Gut Fermentors –
– Hind Gut Fermentors –
« Mouth,
esophagus, stomach, liver, pancreas, gall bladder, and small intestine have
similar functions as compared to monogastrics.
n Large Intestine
► Major
difference between monogastrics and hind gut fermentors is the large intestine
► Large
intestine is exceptionally large and complex compared to monogastrics and
ruminants.
n The
large intestine of hind gut fermentors is analogous to the rumen in ruminants.
► Large,
anaerobic fermentation vat.
► Microbes
digest structural carbohydrates (cellulose, hemicellulose) and soluble
carbohydrates that escape digestion in small intestine to VFA’s.
n VFA’s
absorbed from large intestine and utilized by the animal.
► Microbial
protein produced in large intestine is wasted (only very limited absorption
from large intestine).
n Summary
n There
are three (3) basic types of digestive systems in farm animal species.
► Monogastric
► Ruminant
(cranial fermentor)
► Hind
gut (caudal fermentor)
► The
type of digestive system influences the dietary foodstuffs the animal can
effectively utilize.


03:45
Unknown






















